ARA-290 10mg

R550,00

ARA-290 10mg

ARA-290 10mg

Neuropathic Pain Relief, Anti-inflammatory effects, Tissue protection, Healing, Fatigue, Quality of Life.

R550,00

Out of stock

What It Is?

ARA-290 (also known as Cibinetide) is a lab-made synthetic 11-amino-acid peptide derived from a specific region of erythropoietin (EPO), the natural hormone that stimulates red blood cell production. It was engineered to keep the tissue-protective and anti-inflammatory benefits of EPO while completely removing the blood-boosting (erythropoietic) effects. Developed in the early 2000s by Araim Pharmaceuticals, it targets the innate repair receptor (IRR) to promote healing without raising hematocrit or causing the risks associated with traditional EPO.

Think of ARA-290 as a ‘smart anti-inflammatory repair signal.’ It activates healing pathways without the side effects of full EPO.

How it works (super simple):

– Binds to the innate repair receptor.
– Reduces inflammation, protects nerves and tissues from damage, and promotes repair without stimulating red blood cell production.

  • Neuropathic pain relief – significant reduction in pain and improved nerve function in diabetic neuropathy and sarcoidosis patients.
  • Anti-inflammatory effects – lowers chronic inflammation in autoimmune and inflammatory conditions.
  • Tissue protection & healing – protects nerves, kidneys, heart, and eyes in disease models; potential for wound healing and organ protection.
  • Bonus signals: improved quality of life, reduced fatigue in sarcoidosis, and possible benefits in other inflammatory diseases.
  • In short: It calms harmful inflammation and accelerates repair – especially in nerves and damaged tissues – without affecting blood counts.

ARA-290 showed an excellent safety profile in human trials – very well-tolerated with minimal issues.
In Phase 2 studies: No serious adverse events related to the peptide.

Mild/rare effects:
– Injection-site reactions (redness, mild swelling).
– Occasional headache or fatigue (transient).
– Unknown ultra-long-term effects – trials were relatively short.
– Theoretical risks unproven (e.g., immune modulation in certain conditions).

Bottom line: One of the cleaner research peptides – side effects were rare and mild in studies.

Method of Administration: Subcutaneous into fatty tissue.
Reconstitution: 2ml Bac water into single vial. See Reconstitution Guide
Dose: Research/trial range: 2mg per day (most studies used 2 mg daily or 4 mg three times per week). Use peptide calculator for alternative dosage.

Course: 5 doses @ 2mg per day.

Cycling: 4-12 weeks. Common research use: 4-8 weeks on, then 4 weeks off (or as needed for flare-ups).
Tip: Reconstitute with bacteriostatic water; store in fridge. Use insulin syringes and sterile technique. Start low and monitor symptoms.

  • EPO without the blood boost – designed to keep all the healing benefits of erythropoietin while removing the red-blood-cell-increasing effect.
  • 11-amino-acid precision – tiny but powerful; targets the innate repair receptor (IRR) that normal EPO doesn’t fully activate.
  • Sarcoidosis breakthrough – one of the few compounds shown to improve small-fiber neuropathy symptoms in sarcoidosis patients.
  • Non-hematopoietic hero – the first peptide to separate tissue protection from blood production (a major breakthrough in EPO research).
  • Rapid onset – pain relief in trials started within days to weeks, much faster than many traditional treatments.
  • Research star – still actively studied in 2026 for neuropathy, wound healing, and inflammatory diseases.
    – Nickname in labs often called ‘the smart EPO’ because it heals without the risks of traditional erythropoietin.

Human data comes mainly from completed Phase 2 trials (sarcoidosis, diabetic neuropathy, and other inflammatory conditions).

1. Culver et al. (2017) Phase 2 RCT (sarcoidosis): ARA-290 significantly improved small-fiber neuropathy symptoms and quality of life; well-tolerated.
2. Brines et al. (2014) Phase 2 diabetic neuropathy trial: Reduced neuropathic pain and improved nerve function; excellent safety profile.
3. Dahan et al. (2016) PMC review: ARA-290 as a non-erythropoietic EPO derivative; tissue protection without hematocrit increase.
4. ClinicalTrials.gov ARA-290 studies (referenced 2026): Multiple completed Phase 2 trials for sarcoidosis, neuropathy, and inflammatory conditions.
5. Swolverine research summary (2025–2026): ARA-290 for neuropathic pain and tissue repair; investigational status confirmed.
6. Araim Pharmaceuticals pipeline (historical, referenced 2026): Development focused on IRR activation for chronic inflammatory diseases.
7. PMC mechanistic review (2023, referenced 2026): ARA-290 protects against ischemia-reperfusion injury and promotes healing.
8. Peptide Catalog dosing guide (2026): 1-4 mg daily research protocols; strong safety in trials.
9. DrOracle summary (Feb 2026): Excellent tolerability; no major side effects in human studies; investigational only.
10. Revolution Health overview (2026): Tissue-protective peptide; potential in neuropathy and inflammation without EPO side effects.
Takeaway: Solid Phase 2 human data for neuropathic pain and inflammation; one of the more clinically advanced research peptides, though still unapproved.

Disclaimer Important disclaimer upfront: ARA-290 is NOT approved by the FDA (or any major agency) as of 2026. It remains strictly investigational/research chemical. Phase 2 trials were completed for sarcoidosis, diabetic neuropathy, and other inflammatory conditions, but it never reached full approval. Compounded versions carry quality risks. Long-term safety in healthy people is unknown. It is banned by WADA. Always talk to a doctor – this is not medical advice.
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DISCLAIMER!

All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included and need to be purchased separately. No personal human dosing instructions are provided, only research dosages from clinical studies. We adhere to all local and national (SAHPRA) laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.

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