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Testosterone Boost, Male Fertility, Ovarian Stimulation, Sperm Quantity and Quality, Hypogonadism, TRT Support.
R560,00
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HMG (Human Menopausal Gonadotropin, also known as menotropins; brand names Menopur and Repronex®) is a purified mixture of two natural glycoprotein hormones – follicle-stimulating hormone (FSH) and luteinizing hormone (LH) – extracted from the urine of postmenopausal women. Each vial typically contains roughly equal bioactivity of FSH and LH (75 IU of each in standard formulations). It has been used in fertility medicine since the 1960s and works by directly stimulating the ovaries in women or the testes in men.
Think of HMG as ‘direct fuel’ for the gonads – it bypasses the brain’s signals and supplies ready-made FSH + LH.
How it works
– FSH stimulates egg development in women (follicle growth) or sperm production in men (spermatogenesis).
– LH triggers final egg maturation/ovulation in women or testosterone production in men.
– Ovarian stimulation & IVF success – helps women produce multiple mature eggs for retrieval; improves pregnancy rates in IVF/ICSI cycles.
– Male fertility restoration – when combined with hCG, it induces or restores spermatogenesis in men with hypogonadotropic hypogonadism or during TRT.
– Hypogonadism treatment – boosts natural hormone production and testicular function in men with pituitary issues.
– Bonus signals: supports testicular volume and sperm quality better than hCG alone in some protocols.
In short: It directly powers the ovaries or testes when the body’s own signals are weak or suppressed the go-to for controlled fertility treatments.
Dosing is individualized and highly monitored (ultrasounds + estradiol levels).
Typical dose (subcutaneous or intramuscular injection – belly or thigh):
– Men (off-label fertility/TRT support): 75-150 IU, 2-3 times per week (commonly paired with hCG 250-500 IU 2-3x/week).
Cycling:
– Women: Short, cycle-specific (one treatment cycle lasts ~10-14 days; repeated as needed for IVF).
– Men: Often continuous or long-term (months) while on TRT, or 3-6 month courses for fertility restoration.
Tip: Comes as powder for reconstitution with sterile water). Store in fridge after mixing. Use insulin syringes for comfort.
– Postmenopausal power source: literally made from the urine of women after menopause (rich in FSH/LH because their ovaries have stopped responding).
– IVF workhorse: one of the original ‘superovulation’ drugs that made modern IVF possible.
– Male fertility sidekick – often paired with hCG in men to fully mimic natural FSH + LH for sperm production (better testicular volume than hCG alone).
– 75/75 classic – standard vials deliver ~75 IU FSH + ~75 IU LH – a perfectly balanced ‘menopausal cocktail.’
– Not for dieting – like hCG, it has zero approved role in weight loss despite old misconceptions.
– Multi-baby risk – the powerful stimulation can lead to twins or triplets one reason monitoring is so strict.
– Urine-to-medicine journey – collected, purified, and turned into a life-changing fertility drug for millions of families.
HMG is a true fertility powerhouse – more ‘complete’ than single-hormone options like hCG or gonadorelin when full ovarian or testicular stimulation is needed.
HMG has extensive human data from decades of IVF use and male infertility trials.
1.. WebMD & Cleveland Clinic monographs (2026): Mechanism (FSH + LH), approved uses in IVF/ovulation induction, and side-effect management.
3. Zheng et al. (2025) PMC study: hCG/HMG vs pulsatile GnRH for spermatogenesis in congenital hypogonadotropic hypogonadism similar success rates but hCG/HMG took slightly longer.
4. CNY Fertility & GoodRx clinical overviews (2026): IVF protocols, risks (OHSS, multiples), and real-world success rates.
5. Rao et al. (2025) PMC RCT: Two highly purified HMG preparations (Gynogen HP vs Menopur) showed comparable efficacy and safety in IVF cycles.
6. ScienceDirect overview: HMG definition and role in assisted reproduction urinary-derived FSH/LH combo.
7. Swolverine & The HCG Institute comparisons (20252026): HMG vs hCG/gonadorelin for male fertility and TRT support.
8. WithPower trial summaries (2026): Ongoing research on HMG in ovarian stimulation protocols.
9. Analytical Science Journals mini-review (updated references): HMG as a key FDA-approved ovulation inducer alongside other gonadotropins.
10. DrOracle fertility guide (2026): Fatigue not a common side effect; injection-site reactions and bloating predominate.
Takeaway: Decades of proven efficacy in female IVF + solid evidence for male fertility restoration.
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All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included and need to be purchased separately. No personal human dosing instructions are provided, only research dosages from clinical studies. We adhere to all local and national (SAHPRA) laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.
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