R2 500,00
Fat loss, Metabolic Health, Endurance & Performance, Insulin sensitivity, Glucose Control, Muscle Preservation.
R2 500,00
Out of stock
SLUPP is a lab-made synthetic small molecule — NOT a peptide — with the chemical name 4-Hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino]benzamide (formula C₁₈H₁₄N₂O₂, ~290 g/mol). Developed by researchers at Saint Louis University (hence “SLU”) and advanced at the University of Florida (Thomas Burris lab), it is the first potent pan-agonist of estrogen-related receptors (ERRα, ERRβ, and ERRγ). It was designed to turn on the same metabolic “exercise switches” that endurance training activates in your muscles and mitochondria — essentially an “exercise mimetic in a pill”.
Think of SLU-PP-332 as a molecular “personal trainer” that tells your cells “you just ran a marathon” — even while you’re sitting still.
How it works
• Fat loss and metabolic health — obese mice lost 12% body weight and gained 10× less fat over 1 month (same food intake).
• Endurance & performance — mice ran 45–70% longer and 50% farther; heart muscle strengthened.
• Better insulin sensitivity & glucose control — counters metabolic syndrome features.
• Muscle preservation & mitochondrial boost — potential help for age-related muscle loss or heart failure models.
• Bonus signals: reduced inflammation and possible kidney/heart protection in specific models.
In short: It mimics the metabolic upside of endurance exercise (fat burning, energy production, mitochondrial upgrades) without the workout.
In all published mouse studies, SLU-PP-332 showed an excellent short-term safety profile with no severe toxicities reported.
In preclinical work: No major organ damage, no appetite changes, no obvious behavioral issues.
Theoretical/mild concerns (from reviews and anecdotal gray-market reports):
• Possible mild GI discomfort or energy fluctuations (unconfirmed).
• ERRγ activation could theoretically affect heart muscle long-term (one review notes cardiac hypertrophy risk in other contexts, but not seen here).
• Unknown human effects — no data on liver, kidney, hormones, or long-term uuse.
• Not for pregnancy, heart conditions, or anyone without medical supervision.
Bottom line: Clean in mice so far, but we have no idea how it behaves in people — this is the most experimental compound we’ve covered.
There are no official guidelines because it has never been tested in humans — everything below is from mouse studies or anecdotal reports from unregulated research-chemical vendors.
Typical “research” dose (oral capsules or injection — strictly preclinical/anecdotal):
Cycling (anecdotal only):
• True “exercise in a pill” pioneer — it literally flips the same genetic switches that endurance training does, without you breaking a sweat.
• Not actually a peptide — despite what some shady vendors claim; it’s a tiny synthetic organic molecule (no amino acids!).
• Mice became marathoners — treated normal mice ran 70% longer and 45% farther; obese ones melted fat like they’d been training daily.
• ERR family power — targets “orphan” receptors discovered decades ago that control mitochondria — the first drug to hit all three subtypes effectively.
• Heart failure hope — separate mouse studies showed it restored heart function with almost no muscle loss..
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All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included and need to be purchased separately. No personal human dosing instructions are provided, only research dosages from clinical studies. We adhere to all local and national (SAHPRA) laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.
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