SLU-PP-332 5mg

R550,00

SLU-PP-332 5mg

SLU-PP-332 5mg

Mitochondrial Energy, Fat Loss, Metabolic Health, Endurance, Performance, Improved Insulin Sensitivity, Muscle Preservation, Mitochondrial Boost, Longevity, Organ Protection.

R550,00

Out of stock

What It Is?

SLUPP is a lab-made synthetic small molecule — NOT a peptide — with the chemical name 4-Hydroxy-N-[(Z)-naphthalen-2-ylmethylideneamino]benzamide (formula C₁₈H₁₄N₂O₂, ~290 g/mol). Developed by researchers at Saint Louis University (hence “SLU”) and advanced at the University of Florida (Thomas Burris lab), it is the first potent pan-agonist of estrogen-related receptors (ERRα, ERRβ, and ERRγ). It was designed to turn on the same metabolic “exercise switches” that endurance training activates in your muscles and mitochondria — essentially an “exercise mimetic in a pill”.

Think of SLU-PP-332 as a molecular “personal trainer” that tells your cells “you just ran a marathon” — even while you’re sitting still.

How it works

  • Binds and activates ERRα/β/γ (nuclear receptors that control energy genes).
  • Boosts mitochondrial biogenesis and function, ramps up fatty acid oxidation, and shifts muscle fibers toward endurance type.
  • Increases whole-body energy expenditure without affecting appetite or causing you to move more.

• Fat loss and metabolic health — obese mice lost 12% body weight and gained 10× less fat over 1 month (same food intake).
• Endurance & performance — mice ran 45–70% longer and 50% farther; heart muscle strengthened.
• Better insulin sensitivity & glucose control — counters metabolic syndrome features.
• Muscle preservation & mitochondrial boost — potential help for age-related muscle loss or heart failure models.
• Bonus signals: reduced inflammation and possible kidney/heart protection in specific models.
In short: It mimics the metabolic upside of endurance exercise (fat burning, energy production, mitochondrial upgrades) without the workout.

There are no official guidelines because it has never been tested in humans — everything below is from mouse studies or anecdotal reports from unregulated research-chemical vendors.

Typical “research” dose (oral capsules or injection — strictly preclinical/anecdotal):

For Tablets:  Vendor/anecdotal human protocols (not recommended): 5-20mg per day. Start low and titrate up.

For Injectable: 250mcg/day to start.

Reconstitute 2ml Bac water into vial (See Reconstitution Guide).

Draw 10 Units on 1ml syringe (0.1ml). Subcutaneous administration in the morning.

One vial should last 20 doses.

See Peptide Calculator for alternative Dosing.

Cycling (anecdotal only):

• 4–12 weeks “on,” then 4+ weeks off.
• Often used daily with no formal cycling in gray-market reports.

• True “exercise in a pill” pioneer — it literally flips the same genetic switches that endurance training does, without you breaking a sweat.
• Not actually a peptide — despite what some shady vendors claim; it’s a tiny synthetic organic molecule (no amino acids!).
• Mice became marathoners — treated normal mice ran 70% longer and 45% farther; obese ones melted fat like they’d been training daily.
• ERR family power — targets “orphan” receptors discovered decades ago that control mitochondria — the first drug to hit all three subtypes effectively.
• Heart failure hope — separate mouse studies showed it restored heart function with almost no muscle loss..

  1. Billon et al. (2023) ACS Chemical Biology: First description — SLU-PP-332 induces ERRα-dependent aerobic exercise response and enhances exercise capacity in mice.
    2. Billon et al. (2023) Journal of Pharmacology & Experimental Therapeutics: Synthetic ERR agonist alleviates metabolic syndrome — obese mice lost 12% weight, gained 10× less fat, increased energy expenditure and fatty acid oxidation.
    3. University of Florida News (2023): Summary of weight loss and endurance results; next steps discussed (pill formulation, more animal testing).
    4. Wang et al. (2023) American Journal of Pathology: ERR agonism reverses mitochondrial dysfunction and inflammation in aging kidney (related mechanism).
    5. Eissa et al. (2025) Universal Journal of Pharmaceutical Research: Minireview of SLU-PP-332 and ERR agonists for metabolic regulation and therapeutic potential.
    6. Nasri (2024) Journal of Renal Endocrinology: Discusses weight-loss potential and indirect kidney protection; no significant side effects in studies.
    7. Wikipedia / PubChem entries (2026): Chemical structure confirmation and summary of preclinical work.
    8. Multiple 2025–2026 vendor/research summaries (e.g., Lotilabs, Peptides.org): Note strictly research chemical status with no human trials.
    9. LinkedIn/Dr. Matt Kaeberlein commentary (2025–2026): Warns against off-label use due to lack of human safety/efficacy data.
    10. New Atlas / IFLScience (2023–2024 updates): Popular science coverage of the “exercise pill” mouse results.

 

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DISCLAIMER!

All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included and need to be purchased separately. No personal human dosing instructions are provided, only research dosages from clinical studies. We adhere to all local and national (SAHPRA) laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.

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