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Enhanced Energy, Exercise Performance, Metabolic Health, Glucose Control, Endurance, Physical Capacity, Anti-Aging, Fat-Loss, Inflammation.
R1 160,00
Out of stock
MOTS-c is a lab-made synthetic peptide – a tiny 16-amino-acid chain naturally encoded inside human mitochondrial DNA. It was discovered in 2015 by Dr. Pinchas Cohen’s team at USC and belongs to a special group of ‘mitochondrial-derived peptides’ (MDPs). Think of it as a direct text message from your cell’s power plants (mitochondria) to the nucleus, fine-tuning how your body uses energy, especially during stress or exercise.
Picture MOTS-c as your mitochondria’s ‘exercise-in-a-bottle’ messenger. It flips the same metabolic switches that intense exercise turns on – without you having to move.
How it works:
– Under metabolic stress or exercise, it moves from mitochondria to the nucleus.
– Activates AMPK (the ‘metabolic master switch’) via the folate-AICAR pathway.
– Boosts glucose uptake and fat burning (even without insulin), builds new mitochondria, reduces inflammation, and improves cellular stress resistance.
In short: It makes your cells act like they’re getting regular workouts – even when you’re resting – for better metabolism and resilience.
MOTS-c shows a strong short-term safety profile in the limited data available – no lethal dose found in animals, and the one human analog trial (CB-4211) reported it was ‘safe and well-tolerated.’
In available human pilots and user reports: No serious adverse events.
Mild/rare effects (mostly anecdotal):
– Injection-site redness, swelling, or mild irritation.
– Occasional fatigue or headache (very uncommon).
– Extremely limited long-term human data – almost no large or extended trials.
– Theoretical risks (unproven): possible interference with nucleotide metabolism or folate pathways at very high doses.
No official medical guidelines exist (still experimental), so these come from research protocols, animal scaling, clinic anecdotes, and limited human pilots.
Method of Administration: Subcutaneous into fatty tissue
Reconstitution: 2ml Bac water into single vial. See Reconstitution Guide
Dose: For 10mg Vial: 2mg minimum daily, therefore draw 40 units or 0.4ml.
For 40mg vial, draw 10 units or 0.1ml daily. Many researchers use higher doses for shorter periods.
Use peptide calculator for alternative dosage.
Course: 5 days or 20 days (depending on quantity of vial)
Cycling: 8 weeks on/ 8 weeks off.
Store in Fridge Once reconstituted
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All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included and need to be purchased separately. No personal human dosing instructions are provided, only research dosages from clinical studies. We adhere to all local and national (SAHPRA) laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.
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