R1 150,00
Targeted Visceral Fat Reduction, Improved Body Composition, Liver Fat Reduction, Enhanced Metabolism, Cognitive Enhancement.
R1 150,00
Out of stock
Tesamorelin is a lab-made synthetic 44-amino-acid peptide analog of natural growth hormone-releasing hormone (GHRH). It is the only medication FDA-approved specifically for reducing excess visceral abdominal fat (lipodystrophy) in adults with HIV.
Think of tesamorelin as your pituitary’s ‘natural GH switch.’ It gently wakes up your own growth hormone production instead of adding external GH.
How it works:
-Mimics GHRH – binds receptors on the pituitary gland.
-Triggers short, natural pulses of your own growth hormone (GH) raises IGF-1.
-This preferentially burns deep visceral fat (around organs) while sparing or even increasing lean muscle.
Tesamorelin has a well-established safety profile from large Phase 3 trials and real-world use.
In pivotal studies: Mostly mild-to-moderate and manageable.
Most common:
– Injection-site reactions (redness, itching, swelling, bruising, pain).
– Joint pain (arthralgia), muscle aches (myalgia), pain in arms/legs.
Other reported:
– Peripheral edema (swelling), carpal tunnel symptoms, hypersensitivity reactions.
Bigger caveats:
– May increase blood sugar or worsen glucose control (monitor in diabetics).
– Rare: increased IGF-1-related risks (theoretical cancer concern in high-risk patients).
– Not for active malignancy, pregnancy, or pituitary disorders.
Non-FDA approved for weight loss, muscle, sleep or recovery and therefore no official dosing guidelines.
Method of Administration: Subcutaneous into fatty tissue.
Reconstitution: 2ml Bac water into single vial. See Reconstitution Guide
Dose: 1mg daily taken before bed, therefore 40 units or 0.4ml. Use peptide calculator for alternative dosage.
Course: 5 days.
Cycling: Use for 8-10 week cycles. 4 week break.
Tip: Reconstitute with bacteriostatic water; store in fridge. Use insulin syringes and sterile technique.
Cycle with Ipamorelin.
Tesamorelin has robust human data – two pivotal Phase 3 trials plus long-term extensions and a 2026 meta-analysis.
1. FDA prescribing information (2025 update): Full approved indications, dosing for Egrifta WR, and safety data.
2. Theratechnologies EGRIFTA WR approval announcement (March 2025): New formulation bioequivalent with easier weekly reconstitution.
3. Badran et al. (2026) meta-analysis (Obesity Research & Clinical Practice): Significant VAT reduction (?27.71 cm²), trunk fat loss, lean mass gain (+1.42 kg), and hepatic fat drop; good safety.
4. Stanley et al. (2014) JAMA RCT: Tesamorelin reduced visceral and liver fat in HIV patients with abdominal fat accumulation.
5. Mayo Clinic monograph (2026): Approved dosing (1.282 mg daily), side effects, and HIV lipodystrophy use.
6. Drugs.com Egrifta WR page (2025): Full prescribing details and new formulation advantages.
7. Pivotal Phase 3 pooled analysis (2011): Significant VAT and trunk fat reductions sustained up to 52 weeks.
8. HCP EGRIFTA clinical profile (2026): Patient-reported body image improvements and lean mass gains in trials.
9. Innerbody Research (Jan 2026): Overview of approved use plus off-label signals for visceral fat and body composition.
10. Post-hoc Phase 3 analysis (2023/2026 updates): Equally effective regardless of dorsocervical fat presence.
Takeaway: Gold-standard evidence for its approved indication; one of the best-studied peptides for visceral fat.
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All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included and need to be purchased separately. No personal human dosing instructions are provided, only research dosages from clinical studies. We adhere to all local and national (SAHPRA) laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.
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